BRCA - Breast Back

External References: Wikipedia National Cancer Institute Google Scholar

iCoMut Beta for


Highly significantly mutated genes
PIK3CA
291 patients (32%)
TP53
281 patients (31%)
GATA3
84 patients (9%)
MAP3K1
59 patients (6%)
MLL3
59 patients (6%)
CDH1
57 patients (6%)
NCOR1
34 patients (3%)
MAP2K4
33 patients (3%)
PTEN
31 patients (3%)
RUNX1
25 patients (2%)
PIK3R1
22 patients (2%)
CTCF
20 patients (2%)
AKT1
19 patients (2%)
CBFB
18 patients (2%)
SPEN
18 patients (2%)
SF3B1
17 patients (1%)
ARID1A
17 patients (1%)
RB1
14 patients (1%)
MLL
12 patients (1%)
KRAS
6 patients (0%)
Significantly mutated genes
TBX3
18 patients (2%)
ERBB2
15 patients (1%)
FOXA1
15 patients (1%)
MED23
14 patients (1%)
STAG2
11 patients (1%)
MYB
11 patients (1%)
TBL1XR1
10 patients (1%)
HIST1H3B
10 patients (1%)
CASP8
10 patients (1%)
CDKN1B
7 patients (0%)
CUL4B
7 patients (0%)
RAB40A
6 patients (0%)
Genes near significance
ERBB3
13 patients (1%)
CDC42BPA
12 patients (1%)
SETDB1
10 patients (1%)
FGFR2
8 patients (0%)
GNPTAB
8 patients (0%)
EP300
7 patients (0%)
ACVR1B
6 patients (0%)
Click on a gene to see details.

Notes


• Gene name color indicates: known cancer genes | highly compelling novel candidate cancer genes | other candidates

Data details


Mutation list for BRCA
Q-Q plots for BRCA