FOXA1 Back

forkhead box A1

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NCBI Description of FOXA1
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of FOXA1 Add / Edit FOXA1: Annotations

No community annotations yet for FOXA1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FOXA1 is highly significantly mutated in
FOXA1 is significantly mutated in
Breast
BRCA
15 patients (1%)
FOXA1 is near significance in
Prostate
PRAD
4 patients (2%)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FOXA1