WASF3 Back

WAS protein family, member 3

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NCBI Description of WASF3
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.

Community Annotation of WASF3 Add / Edit WASF3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WASF3 is highly significantly mutated in
WASF3 is significantly mutated in
Melanoma
MEL
8 patients (6%)
WASF3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WASF3