NCBI Description of U2AF1
|This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.|
Community Annotation of U2AF1 Add / Edit U2AF1: Annotations
No community annotations yet for U2AF1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.