NCBI Description of TNFRSF14
|The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.|
Community Annotation of TNFRSF14 Add / Edit TNFRSF14: Annotations
No community annotations yet for TNFRSF14.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.