STX2 Back

syntaxin 2

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NCBI Description of STX2
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of STX2 Add / Edit STX2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STX2 is highly significantly mutated in
STX2 is significantly mutated in
Lung adenocarcinoma
LUAD
8 patients (1%)
STX2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for STX2