SOX17 Back

SRY (sex determining region Y)-box 17

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NCBI Description of SOX17

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.

Community Annotation of SOX17 Add / Edit SOX17: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SOX17 is highly significantly mutated in
SOX17 is significantly mutated in
11 patients (4%)
SOX17 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SOX17