SLC25A5 Back

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5

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NCBI Description of SLC25A5
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.

Community Annotation of SLC25A5 Add / Edit SLC25A5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC25A5 is highly significantly mutated in
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SLC25A5 is significantly mutated in
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SLC25A5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC25A5