SEPT12 Back

septin 12

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NCBI Description of SEPT12

This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SEPT12 is highly significantly mutated in
SEPT12 is significantly mutated in
combined cohort
31 patients (0%)
SEPT12 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SEPT12