RRAS2 Back

related RAS viral (r-ras) oncogene homolog 2

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NCBI Description of RRAS2
This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.

Community Annotation of RRAS2 Add / Edit RRAS2: Annotations

No community annotations yet for RRAS2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RRAS2 is highly significantly mutated in
RRAS2 is significantly mutated in
RRAS2 is near significance in
Endometrial
UCEC
4 patients (1%)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RRAS2