PTPN11 Back

protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PTPN11

Community Annotation of PTPN11 Add / Edit PTPN11: Annotations

No community annotations yet for PTPN11.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PTPN11 is highly significantly mutated in
Acute myeloid leukemia
AML
10 patients (5%)
PTPN11 is significantly mutated in
PTPN11 is near significance in
Neuroblastoma
NB
3 patients (3%)
Glioblastoma multiforme
GBM
5 patients (1%)
Multiple myeloma
MM
3 patients (1%)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PTPN11