POU2F2 Back

POU class 2 homeobox 2

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NCBI Description of POU2F2
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of POU2F2 Add / Edit POU2F2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POU2F2 is highly significantly mutated in
POU2F2 is significantly mutated in
Diffuse large B-cell lymphoma
DLBCL
4 patients (6%)
POU2F2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for POU2F2