OR8B8 Back

olfactory receptor, family 8, subfamily B, member 8

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NCBI Description of OR8B8
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

OR8B8 is highly significantly mutated in
OR8B8 is significantly mutated in
OR8B8 is near significance in
Endometrial
UCEC
7 patients (2%)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for OR8B8