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NCBI Description of MYOCD

This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MYOCD Add / Edit MYOCD: Annotations

No community annotations yet for MYOCD.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MYOCD is highly significantly mutated in
MYOCD is significantly mutated in
18 patients (15%)
MYOCD is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MYOCD