MYCN Back

v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

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NCBI Description of MYCN
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Community Annotation of MYCN Add / Edit MYCN: Annotations

No community annotations yet for MYCN.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MYCN is highly significantly mutated in
MYCN is significantly mutated in
Endometrial
UCEC
7 patients (2%)
MYCN is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MYCN