MLL2 Back

myeloid/lymphoid or mixed-lineage leukemia 2

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NCBI Description of MLL2

Community Annotation of MLL2 Add / Edit MLL2: Annotations

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Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MLL2 is highly significantly mutated in
Bladder
BLCA
26 patients (26%)
Diffuse large B-cell lymphoma
DLBCL
12 patients (20%)
Lung squamous cell carcinoma
LUSC
36 patients (20%)
Head and neck
HNSC
59 patients (15%)
combined cohort
PanCan
270 patients (5%)
MLL2 is significantly mutated in
MLL2 is near significance in
Medulloblastoma
MED
4 patients (4%)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MLL2