KEL Back

Kell blood group, metallo-endopeptidase

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NCBI Description of KEL

This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KEL is highly significantly mutated in
KEL is significantly mutated in
Glioblastoma multiforme
15 patients (5%)
KEL is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KEL