ING1 Back

inhibitor of growth family, member 1

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NCBI Description of ING1
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Community Annotation of ING1 Add / Edit ING1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ING1 is highly significantly mutated in
Endometrial
UCEC
13 patients (5%)
ING1 is significantly mutated in
ING1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ING1