HSP90AB1 Back

heat shock protein 90kDa alpha (cytosolic), class B member 1

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NCBI Description of HSP90AB1

This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.

Community Annotation of HSP90AB1 Add / Edit HSP90AB1: Annotations

No community annotations yet for HSP90AB1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


HSP90AB1 is highly significantly mutated in
HSP90AB1 is significantly mutated in
combined cohort
51 patients (1%)
HSP90AB1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for HSP90AB1