HOXA11 Back

homeobox A11

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of HOXA11
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Community Annotation of HOXA11 Add / Edit HOXA11: Annotations

No community annotations yet for HOXA11.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

HOXA11 is highly significantly mutated in
(none)
HOXA11 is significantly mutated in
(none)
HOXA11 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for HOXA11