ERC1 Back

ELKS/RAB6-interacting/CAST family member 1

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NCBI Description of ERC1
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ERC1 Add / Edit ERC1: Annotations

No community annotations yet for ERC1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ERC1 is highly significantly mutated in
(none)
ERC1 is significantly mutated in
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ERC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ERC1