CD79B Back

CD79b molecule, immunoglobulin-associated beta

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NCBI Description of CD79B
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Community Annotation of CD79B Add / Edit CD79B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CD79B is highly significantly mutated in
Diffuse large B-cell lymphoma
DLBCL
7 patients (12%)
CD79B is significantly mutated in
CD79B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CD79B