S-adenosylhomocysteine hydrolase-like 1

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NCBI Description of AHCYL1

The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of AHCYL1 Add / Edit AHCYL1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AHCYL1 is highly significantly mutated in
AHCYL1 is significantly mutated in
AHCYL1 is near significance in
7 patients (2%)

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AHCYL1